Generally, no. As the FAQ says you need colliders to capture touch points — http://interactivelab.github.io/TouchScript/#faq. But there are ways to do this manually: 1. You can place invisible objects with collders on them right behind gui elements. These objects will get touch points effectively covering the cube. 2. Write a custom script inherited from HitTest which checks coordinates in screen space and discards touch points if they are in selected areas where your gui elements are.