Remove game object from base prefab. Leave it in derived prefabs.

As title suggests, is there a way to remove game object from base prefab but still keep it in all derived prefabs.

I'm asking since my workflow is usually creation of one prefab (think one type of unit) and than making more base prefabs chain out of it. This base prefabs are used for other types of final prefabs.

[Edit]
I have made a mistake previously, naturally I make more base prefabs than derived. It is edited right now.
[/Edit]