Referencing things inside a prefab?

I don't use prefabs too much, but I think they will do what I need to build a dynamic scrollable list. Problem is, I don't really know the right way to reference the components within the prefab.

For instance, I have an image, a text field, and a button that are all children of an empty GO and that is my prefab. When I instantiate it do I then use GetComponentInChildren to get the image? That seems wrong - and then what if I have two buttons or two images?