question about destroy gameobject in Addressable

If I use the api Addressables.LoadSceneAsync to load a scene, how i destroy the gameObject belong to this scene. I means this gameObject is instantiated at the same time when the scene is loaded, it's part of the scene.

 

Pretty sure you just destroy them as normal. What are you worried about exactly?

 

I just worry about if I using the normal API GameObject.Destroy(), maybe i will break the rule to cause something asset can't unload. The document explain the reference count, the load or unload of the asset is depending on the reference count inside addressable system. I just want to make sure the which way to destroy is right.