Question Python-Unity communication with frame-sync

I would like to make machine learning project in Unity but the thing is I want machine learning agent to be implemented in python script because I am well experienced in pytorch and I don't really want to learn unity ml agents, python is much more universal. I would like unity to communicate with python in ping-pong manner. Unity gameObject AiController would send neural net inputs and receive neural net output in a frame basis. How can I make unity and python communicate "inside" Update method in my AiController monobehaviour?