How do I animate an albedo texture on a mesh?

Hello. I use 2017.2. I have a low poly mesh(head of a woman) and I want to apply an animated albedo on it. For example after some seconds play an animation where she blinks, or play by script an albedo animation like she speaks.

I don't know how to draw and format the UV albedo texture in import options, and I don't know how to script the animation. Frankly I have no idea if this is even possible. But I don't want to add geometry to the mesh with blend shapes for blinking or speaking, I want just to draw and animate the 2D albedo map on the face.

Sorry for my bad english.