Animate 2 characters in prefabs

Hello,
I would like to start using Unity by making a very short and not complicated animation, only using content already available.

I would download a room and 2 characters.
The clip would only last a few seconds, I would make close ups on the hand of a character, caressing the forehead of the other character, then a close up on the mouth of the first character and make her smile.

I would record using ShadowPlay.

But is it possible?
If so, how can I take the corners of the mouth, for example, and decide their position on a time scale, then make a new position?

Thank you

 

hello?

 

Yes.

Research blend shapes, mouth shapes in DCC applications like Blender.