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Yes it is possible with shader graph. When you are using sample texture 2d node you can change uv parameter here. Also when you generating...
Steamvr has script called UIElement and it works for buttons. Try it on slider. Don't forget to add a collider.
You can open up Interactions example scene and simple interactable is what you need. Just check out script attached to it.
It is working for me (2019.3, UniversalRP)